Indicators on APZ777 You Should Know
Indicators on APZ777 You Should Know
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APZ777
まずは、アリピプラゾールの作用の特徴をまとめたいと思います。専門用語も出てきますが、後ほど詳しく説明していますので、わからないところは読み飛ばしてください。
アリピプラゾールは統合失調症のお薬として発売されましたが、相次いで躁症状やうつ症状に対して適応が認められました。
また、過食症状の軽減に役立つこともあります。アリピプラゾールはどちらかというと食欲が減少する方が多いお薬です。過食症状はいろいろな原因で認められることがあるので、一概にアリピプラゾールが効果があるとは言えませんが、ひとつの治療の選択肢となっています。アリピプラゾールを低用量で使うと、過食衝動が落ち着く方がいらっしゃいます。
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うつ病では、モノアミンと呼ばれるセロトニン・ノルアドレナリン・ドパミンが足りなくなっていると考えられています。アリピプラゾールでは、低用量でドパミンを増やす作用があります。さらに、セロトニン1A受容体を少しだけ刺激する作用があります。このため、ドパミンだけでなくセロトニンの増加も期待できます。